The Starstone carried by the Hei Ten Shi when it was sabotaged and presumably destroyed. This Starstone is releasing pulses of radiation that are bouncing off of the Earth's ionosphere. This radiation overloads immortal cells, causing them to malfunction and eventually killing them. This is the affliction threatening every immortal on Earth and it is also the affliction that is killing Amelia Orsel. Macallan's primary goal is to shut off the malfunctioning Starstone.